D51 Counterregulation in skeletal vascular bed during effective treatment of essential hypertensives with verapamil
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15 صفحه اولAlterations in aldosterone biosynthesis in essential hypertensives.
We studied hypertensives with decreased adrenal responsiveness to infused angiotensin II (AII) to assess their responsiveness to other aldosterone secretagogues, ACTH and potassium, which are thought to stimulate aldosterone synthesis in sites different from one another and from AII. All subjects, following sodium restriction, received an infusion of AII in increasing doses (0.1-3 ng/kg per min...
متن کاملCircadian Variation of Blood Pressure is Correlated to Vascular Endothelial Function in Nondiabetic Essential Hypertensives
Background: Hypertension is associated with altered endothelial nitric oxide (NO) release. Abnormal endotheliumdependent vascular relaxation in patients with primary hypertension has been described and is associated with abnormalities of the NO system. Little is known about the relationship between the circadian rhythm of blood pressure (BP) and endothelial function in patients with essential h...
متن کاملCoronary artery spasm during exercise: treatment with verapamil.
Six patients who had documented coronary spasm and no coronary artery with organic obstruction greater than 50% developed angina and ST-segment elevation on exercise testing. Oral verapamil, 160-480 mg/day, prevented exercise-induced ischemia in all patients and increased maximal work capacity from 611+/- 250 kpm to 808 +/- 160 kpm (p less than 0.02). In two patients, a relationship between the...
متن کاملCardiovascular effects of verapamil in patients with essential hypertension.
The cardiovascular effects of intravenous verapamil and 3 months of oral administration of a slow-release form of verapamil (verapamil-SR) were studied in 10 patients with mild-to-moderate essential hypertension. Intravenous verapamil reduced arterial pressure by 15% (p less than .01) through a fall in total peripheral resistance of 29% (p less than .01); provoked a reflexive rise in heart rate...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 1997
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(97)89080-2